O-186 Paternal age is significantly related with the type of delivery and the sex of the newborn in IVF or ICSI cycles with donated oocytes

Abstract Study question Does paternal age have any effect on obstetric and perinatal outcomes in in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) cycles with donated oocytes? Summary answer Newborn sex and type of delivery, but not other obstetric and perinatal outcomes measured, were significantly different when comparing our paternal age groups. What is known already Currently there is a delay in fatherhood that has led to an increase of the average male age at which the first child is conceived. Studies relating paternal age with reproductive risks are increasing and results are controversial leading to a need of more research about it, which this study tries to address. Studies considering treatments with donated oocytes (controlled female factor) allow for a better understanding of male factor and reproductive risks. These risks for the mother and offspring need to be properly assessed and therefore it is important to study whether they can be affected by paternal age. Study design, size, duration This retrospective observational multicentric cohort study has considered pregnancies and children conceived from donor IVF-ICSI performed to couples in Spain IVIRMA clinics between January 2008 and March 2020 using patients’ own sperm. Paternal age ranged from 21 to 54 years. The study population was divided in three groups: 40(C) years. The data available and included consisted of 16382 patients who had a delivery with a live birth and 17988 singleton newborns. Participants/materials, setting, methods We evaluated pregnancies and children from donor IVF-ICSI with own semen, known age and resulting in a delivery. Data were obtained from the patient’s clinical charts to build the database to analyze the main outcomes of the study. P