P1834Surgical treatment of ischemic heart failure in men and women: a large single center comparison

Abstract Background Femal sex and heart failure (HF) are traditionally considered poor prognostic factors for surgery. However, the influence of patient sex on outcomes following cardiac surgery is proving controversial and the current guidelines are lacking in providing specific indications. Purpose We aimed to investigate the association of sex on outcomes of a large, single-center population with ischemic left ventricular dysfunction undergoing coronary artery bypass grafting (CABG) plus surgical ventricular reconstruction (SVR) with or without mitral valve surgery. Methods From July 2001 to June 2017, 648 patients (111 women [17%] and 537 men [83%]) with previous myocardial infarction, LV remodeling and HF were referred to our Center for cardiac surgery. Follow-up continued through June 2018. All patients underwent SVR; CABG was performed in 582 patients (90%) and mitral valve surgery in 200 patients (30%). Primary outcome was defined the time to death from any cause, including death within 30 days. Secondary outcome included death from any cause at 30 days or hospitalization for any cause. Results At baseline, women were older (67.7±9.56 versus 63.9±9.43, P