P6259Unfavourable vascular risk profile of smokers with testosterone deficiency

Abstract Purpose Testosterone deficiency and cigarette smoking are both associated with increased cardiovascular (CV) mortality risk. We examined whether vascular function and structure parameters are significantly impaired in smokers with low testosterone levels. Methods Carotid intima media thickn...

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Veröffentlicht in:European heart journal 2019-10, Vol.40 (Supplement_1)
Hauptverfasser: Ioakeimidis, N, Vlachopoulos, C, Georgakopoulos, C, Angelis, A, Terentes-Printzios, D, Sigala, E, Rokkas, K, Katsi, V, Tousoulis, D
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Sprache:eng
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Zusammenfassung:Abstract Purpose Testosterone deficiency and cigarette smoking are both associated with increased cardiovascular (CV) mortality risk. We examined whether vascular function and structure parameters are significantly impaired in smokers with low testosterone levels. Methods Carotid intima media thickness (cIMT) and aortic pulse wave velocity (aPWV) were measured in a total of 690 patients (mean 58±7 yrs) without manifest CV/atherosclerotic disease. All patients underwent exercise stress test (and coronary angiography) to reveal coronary artery disease (CAD). Plasma total testosterone (TT) levels were measured in all patients. Results Participants were divided into four subgroups according to smoking (yes/no) and measured low or normal TT levels (low TT
ISSN:0195-668X
1522-9645
DOI:10.1093/eurheartj/ehz746.0859