P3384Left atrial appendage pseudo-thrombus as an independent risk factor for ischaemic stroke in patients with non-valvular atrial fibrillation

Abstract Background Left atrial appendage (LAA) pseudo-thrombus is a well recognised phenomenon in patients with atrial fibrillation (AF) undergoing cardiovascular CT (CCT). The clinical significance of LAA pseudothrombus on CCT, in those with non-valvular AF (NVAF) is unknown. Objectives To determine the association of LAA pseudo-thrombus in those with NVAF and ischaemic stroke. Methods 216 consecutive patients with NVAF, referred for CCT (with both standard and 60-second delayed acquisitions) were assessed for the LAA pseudo-thrombus, LA and LAA dimensions and morphology, cardiovascular risk factors, treatment, and ischaemic stroke risk Results Mean age (±SD) was 65.0±10.6 years (range 32–89) and 70.8% were male. LAA pseudo-thrombus was present in 59/216 (27%) patients. Ischaemic stroke is more frequent with increasing age (OR 1.10 (95% confidence intervals (CI) 1.06, 1.16), p