Asian dust exposure triggers acute myocardial infarction

To elucidate whether Asian dust is associated with the incidence of acute myocardial infarction (AMI) and to clarify whether patients who are highly sensitive to Asian dust will develop AMI. Twenty-one participating institutions located throughout Kumamoto Prefecture and capable of performing corona...

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Veröffentlicht in:European heart journal 2017-11, Vol.38 (43), p.3202-3208
Hauptverfasser: Kojima, Sunao, Michikawa, Takehiro, Ueda, Kayo, Sakamoto, Tetsuo, Matsui, Kunihiko, Kojima, Tomoko, Tsujita, Kenichi, Ogawa, Hisao, Nitta, Hiroshi, Takami, Akinori
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Sprache:eng
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Zusammenfassung:To elucidate whether Asian dust is associated with the incidence of acute myocardial infarction (AMI) and to clarify whether patients who are highly sensitive to Asian dust will develop AMI. Twenty-one participating institutions located throughout Kumamoto Prefecture and capable of performing coronary intervention were included in the study. Data for ground-level observations of Asian dust events were measured at the Kumamoto Local Meteorological Observatory. Data collected between 1 April 2010 and 31 March 2015 were analysed, and 3713 consecutive AMI patients were included. A time-stratified case-crossover design was applied to examine the association between Asian dust exposure and AMI. The occurrence of Asian dust events at 1 day before the onset of AMI was associated with the incidence of AMI [odds ratio (OR), 1.46; 95% confidence interval (CI), 1.09-1.95] and especially, non-ST-segment elevation myocardial infarction was significant (OR 2.03; 95% CI, 1.30-3.15). A significant association between AMI and Asian dust was observed in patients with age ≥75 years, male sex, hypertension, diabetes mellitus, never-smoking status, and chronic kidney disease (CKD). However, Asian dust events had a great impact on AMI onset in patients with CKD (P 
ISSN:0195-668X
1522-9645
DOI:10.1093/eurheartj/ehx509