Prognostic value of global coronary flow reserve improvement after percutaneous coronary intervention in patients with chronic coronary syndrome

Abstract Background Impaired global coronary flow reserve (g-CFR) evaluated by phase-contrast cine cardiovascular magnetic resonance (PC-CMR) has been reported to be associated with worse outcomes in patients with cardiovascular disease. Purpose This study aimed to evaluate the prognostic value of g...

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Veröffentlicht in:European heart journal 2023-11, Vol.44 (Supplement_2)
Hauptverfasser: Nogami, K, Hoshino, M, Usui, E, Hada, M, Hanyu, Y, Nagamine, T, Ueno, H, Matsuda, K, Sakamoto, T, Kakuta, T
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Sprache:eng
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Zusammenfassung:Abstract Background Impaired global coronary flow reserve (g-CFR) evaluated by phase-contrast cine cardiovascular magnetic resonance (PC-CMR) has been reported to be associated with worse outcomes in patients with cardiovascular disease. Purpose This study aimed to evaluate the prognostic value of g-CFR improvement evaluated by PC-CMR in patients with chronic coronary syndrome (CCS). Methods A total of 320 patients with CCS who underwent pre- and post-PCI PC-CMR measurements and stress perfusion CMR were followed-up to determine the predictors of major adverse cardiovascular events (MACE). The association between CMR variables including changes in G-CFR after PCI and MACE (cardiac death, nonfatal myocardial infarction, hospitalization for heart failure, or ischemic stroke) was investigated. Results G-CFR improvement was observed in 162 (50.6%) and MACE occurred in 26 (8.1%) during follow-up (2.5 year, 1.3-4.0). G-CFR improvement was significantly associated with lower pre-PCI G-CFR (p
ISSN:0195-668X
1522-9645
DOI:10.1093/eurheartj/ehad655.219