Clinical picture and laboratory disorders in adult patients with pre-existing cardiomyopathy and COVID infection

Abstract COVID infection is presented with different clinical manifestations in different population groups. A number of studies have shown increased mortality in patients with pre-existing cardiomyopathy, which is common in the elderly population. Patients with COVID infection have an increased incidence of cardiac disease, most commonly myocarditis, acute heart failure and coagulation dysfunction seen after an increase in the value of D-dimer. Methods We analyzed the data of patients hospitalized in our institution for a period of one month (December 2020), positive for COVID 19 virus, with the presence of cardiomyopathy and associated comorbidity, their clinical picture, as well as laboratory tests - with reference to inflammatory markers and D-dimer. Results During the study period, 53 patients were positive for COVID infection. The average age of the patients was 76.01 years. Total mortality was 17.78% (45 patients recovered, while 8 died). We divided the patients into 2 groups - patients with cardiomyopathy before COVID infection and those who did not have it. In the first group 30 patients were included with compensated cardiomyopathy with drugs before COVID infection, and in the second group 23 patients were included without cardiomyopathy. The clinical picture in 75.5% of patients was moderate, in 11.3% it was severe with reduced saturation