Predictive value of the left ventricular function in coronary artery disease: should we tailor risk-stratification for men and women?

Abstract Introduction Left ventricular function (LVF) is a well-known recognized predictor of major adverse cardiovascular events (MACE) in patients with coronary artery disease (CAD) and is recommended in all CAD patients by the guidelines of the European Society of Cardiology. As non-obstructive CAD is more common among women, the predictive value of LVF might differ between men and women. Purpose The aim of this study is to evaluate sex-related differences in the predictive value of LVF in patients with suspected or documented CAD. Methods Patients with suspected or documented CAD who underwent transthoracic echocardiography (TTE) with LVF assessment in a tertiary center between 2014 and 2021 were included. LVF was classified with left ventricular ejection fraction (LVEF) as normal (≥52%) or impaired (LVEF