Characteristics, predictors and outcomes after unprotected left main stem primary percutaneous coronary intervention

Abstract Background Reports about outcomes of patients undergoing primary percutaneous coronary intervention (PCI) for unprotected left main (ULM) coronary artery are limited. We aimed to investigate the characteristics, in-hospital and the long-term outcomes of these patients. Methods From a high-volume, single-centre, prospective registry, in a period from 2009–2019, we identified 111 pts (0.96%) who undergone primary PCI for ULM culprit lesion. The short- and the long-term outcomes in this subset was evaluated and compared to 9463 (82.5%) patients undergoing pPCI for lesions located in other segments (Non-LM group). Technical success was defined as final TIMI 3 flow in both, left main and distal vessels, anterior descending and circumflex artery, without significant residual stenosis (>20% following balloon angioplasty or stent implantation) and side branch compromise (residual stenosis >75%). Results Patients with ULM were older and more likely to present as Non-ST-elevation MI (77% vs. 93%; p