Gemella morbillorum asa Cause of Septic Shock

The gram-positive bacterium Gemella morbillorum has been recovered from patients with endocarditis but has rarely been associated with acute fulminant infections. We describe two children with a rapid onset of septic shock, which was fatal in one, following infection with this organism. G. morbillor...

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Veröffentlicht in:Clinical infectious diseases 1996-06, Vol.22 (6), p.1084-1086
Hauptverfasser: Vasishtha, Sanjeev, Isenberg, Henry D., Sood, Sunil K.
Format: Artikel
Sprache:eng
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Zusammenfassung:The gram-positive bacterium Gemella morbillorum has been recovered from patients with endocarditis but has rarely been associated with acute fulminant infections. We describe two children with a rapid onset of septic shock, which was fatal in one, following infection with this organism. G. morbillorum is a commensal organism of the upper respiratory tract; it gained access to the bloodstreams in these patients, and bacteremia occurred. A clinical drawback is that the initial colonial morphology of this organism leads to presumptive identification as a viridans streptococcus, an organism not commonly associated with septic shock syndrome. Resistance of G. morbillorum to penicillin appears to be common; therefore, initial empirical combination therapy (a β-lactam agent and an aminoglycoside) or vancomycin treatment should be considered.
ISSN:1058-4838
1537-6591
DOI:10.1093/clinids/22.6.1084