THE EFFECT OF BLOOD FLOW UPON THE ACTIVITY OF GALLAMINE TRIETHIODIDE

The onset, depth and recovery from paralysis produced by gallamine triethiodide were studied using the tibialis anterior muscle/sciatic nerve preparation in mongrel dogs, during changes in blood flow to this muscle. A roller pump was used to effect the blood flow changes via an aorto-femoral shunt....

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Veröffentlicht in:	British journal of anaesthesia : BJA 1976-02, Vol.48 (2), p.69-73
Hauptverfasser:	GOAT, V.A., YEUNG, M.L., BLAKENEY, C., FELDMAN, S.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Flow Velocity Body Temperature Cardiac Output Gallamine Triethiodide - adverse effects Gallamine Triethiodide - blood Muscles - blood supply Muscles - drug effects Paralysis - chemically induced Regional Blood Flow Time Factors
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Beschreibung
Zusammenfassung:	The onset, depth and recovery from paralysis produced by gallamine triethiodide were studied using the tibialis anterior muscle/sciatic nerve preparation in mongrel dogs, during changes in blood flow to this muscle. A roller pump was used to effect the blood flow changes via an aorto-femoral shunt. The onset and depth of paralysis were related directly to muscle blood flow. There was no correlation between the rate of recovery from paralysis and the blood flow to the muscle.
ISSN:	0007-0912 1471-6771
DOI:	10.1093/bja/48.2.69