NEPHROTOXICITY FROM METHOXYFLURANE ANAESTHESIA: A 6-YEAR RETROSPECTIVE STUDY

NEPHROTOXICITY FROM METHOXYFLURANE ANAESTHESIA: A 6-YEAR RETROSPECTIVE STUDY

Methoxyflurane was administered to 1196 patients during a 6-year period and the records of 1000 patients were reviewed. Two patients developed severe renal insufficiency but survived. There were 17 other patients who showed an inappropriate postoperative diuresis but they did not develop severe rena...

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Veröffentlicht in:British journal of anaesthesia : BJA 1973-04, Vol.45 (4), p.358-362
Hauptverfasser: URGENA, R. B., GERGIS, S. D.
Format: Artikel
Sprache:eng
Schlagworte:
Anesthesia, Inhalation
Diuresis
Humans
Kidney Diseases - chemically induced
Male
Methoxyflurane - adverse effects
Middle Aged
Postoperative Complications
Retrospective Studies
Water-Electrolyte Balance
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Zusammenfassung:Methoxyflurane was administered to 1196 patients during a 6-year period and the records of 1000 patients were reviewed. Two patients developed severe renal insufficiency but survived. There were 17 other patients who showed an inappropriate postoperative diuresis but they did not develop severe renal insufficiency. The records of 1000 patients given general anaesthesia other than methoxyflurane were also studied. None exhibited inappropriate diuresis. The mortality rate from all causes was comparable in the two groups.
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/45.4.358