The Prognostic Significance of Established Hematological Parameters and Inflammatory Biomarkers in Assessing Dengue Infection Severity and Progression among Patients Ages 5 to 14 in a Tertiary Government Hospital in Pampanga, Philippines

Abstract Introduction/Objective Dengue virus (DENV) is an arthropod-borne virus which imposes a significant burden on the health system in most tropical and subtropical countries. In 2009, WHO classified Dengue into Dengue Without Warning Signs (DNWS), Dengue With Warning Signs (DWWS), and Severe De...

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Veröffentlicht in:American journal of clinical pathology 2021-10, Vol.156 (Supplement_1), p.S103-S104
Hauptverfasser: Cai, J R, Camacho, I B, Caras, E M, Carayugan, J A, Carmona, K H, Castillo, C O, Castillo, E D, Nieto, X A, Sison, R G
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Sprache:eng
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Zusammenfassung:Abstract Introduction/Objective Dengue virus (DENV) is an arthropod-borne virus which imposes a significant burden on the health system in most tropical and subtropical countries. In 2009, WHO classified Dengue into Dengue Without Warning Signs (DNWS), Dengue With Warning Signs (DWWS), and Severe Dengue (SD). This study aims to establish the prognostic value of predetermined hematological parameters and inflammatory biomarkers in assessing severity and progression of dengue infection among ages 5-14. Methods/Case Report A retrospective study was conducted to evaluate the Complete Blood Count, Inflammation biomarkers, and severity of dengue patients (5-14 of age). The diagnosis must be serologically confirmed by a positive NS1/IgM. Results (if a Case Study enter NA) A total of 36 patients participated in the study, having 18 from each groups of DWWS and SD. The mean age of Dengue cohort was 13.9 years with 59% (19/36) being male. Laboratory findings reveal SD to have lower platelet count (
ISSN:0002-9173
1943-7722
DOI:10.1093/ajcp/aqab191.220