Investigating the Effect of Thyroid Nodule Location on the Risk of Thyroid Cancer
Background: Thyroid nodules are routinely evaluated with ultrasound. Our aim was to determine if thyroid nodule location was a useful feature to predict thyroid cancer. Materials and Methods: Retrospective review of patients with thyroid nodules from six referral centers from 2006 to 2010. A total o...
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| Veröffentlicht in: | Thyroid (New York, N.Y.) N.Y.), 2020-03, Vol.30 (3), p.41-407 |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
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| Zusammenfassung: | Background:
Thyroid nodules are routinely evaluated with ultrasound. Our aim was to determine if thyroid nodule location was a useful feature to predict thyroid cancer.
Materials and Methods:
Retrospective review of patients with thyroid nodules from six referral centers from 2006 to 2010. A total of 3313 adult patients with thyroid nodules and confirmed benign or malignant thyroid diagnoses were included.
Results:
Mean patient age was 54.2 (18–97) years, and the majority were women (
n
= 2635, 79.8%). A total of 3241 nodules were analyzed, 335 (10.3%) of which were malignant. Thyroid nodule location was an independent risk factor in predicting thyroid cancer (
p
= 0.005). Thyroid cancer odds were highest in the isthmus (odds ratio [OR] = 2.4, 95% confidence interval [CI] 1.6–3.6,
p
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| ISSN: | 1050-7256 1557-9077 1557-9077 |
| DOI: | 10.1089/thy.2019.0478 |