The Regulatory Effect of VEGF-Ax on Rat Bone Marrow Mesenchymal Stem Cells' Angioblastic Differentiation and Its Proangiogenic Ability

Vascular endothelial growth factor A (VEGFA), which plays a key role in angiogenesis, is composed of many isoforms. Distinct VEGFA isoforms are generated by alternative splicing of VEGFA mRNA and named as VEGF xxx , where xxx represents the number of amino acids present in the final protein sequence...

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Veröffentlicht in:	Stem cells and development 2020-05, Vol.29 (10), p.667-677
Hauptverfasser:	Li, Jianjun, Li, Zhihao, Wang, Chengqiang, Li, Zhijia, Xu, Haixia, Hu, Yunteng, Tan, Zhiwen, Zhang, Fu, Liu, Chun, Yang, Minsheng, Wang, Yihan, Jin, Yanglei, Peng, Ziyue, Biswas, Sourabh, Zhu, Lixin
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing - drug effects Angiogenesis Inhibitors - pharmacology Animals Bone Marrow Cells - drug effects Bone Marrow Cells - metabolism Cell Differentiation - drug effects Cell Differentiation - physiology Endothelial Cells - drug effects Endothelial Cells - metabolism Mesenchymal Stem Cells - drug effects Mesenchymal Stem Cells - metabolism Neovascularization, Physiologic - drug effects Neovascularization, Physiologic - physiology Original Research Reports Rats, Sprague-Dawley Vascular Endothelial Growth Factor A - metabolism
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