Low Infectious Morbidity after Intensive Chemotherapy and Autologous Peripheral Blood Progenitor Cell Transplantation in the Outpatient Setting for Women with Breast Cancer

Low Infectious Morbidity after Intensive Chemotherapy and Autologous Peripheral Blood Progenitor Cell Transplantation in the Outpatient Setting for Women with Breast Cancer

Autologous peripheral blood progenitor cell (PBPC) transplantation is increasingly employed in the outpatient setting, yet data on early complications following PBPC transplantation are scant. We evaluated 105 women with high-risk primary or metastatic breast cancer who were treated at a single inst...

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Veröffentlicht in:Clinical infectious diseases 2001-02, Vol.32 (4), p.546-551
Hauptverfasser: Chandrasekar, P. H., Abraham, O. C., Klein, J., Alangaden, George, Chalasani, G., Cassells, L., Dansey, R., Abella, S., Karanes, C., Peters, W., Baynes, R.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Ambulatory Care
Ambulatory Care Facilities
Anti-Infective Agents - therapeutic use
Antibiotic Prophylaxis
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Bacteremia
Biological and medical sciences
Blood
Bone marrow
Breast cancer
Breast Neoplasms - therapy
Carmustine - therapeutic use
Chemotherapy
Cisplatin - therapeutic use
Combined Modality Therapy
Cyclophosphamide - therapeutic use
Female
Fever
Gynecology. Andrology. Obstetrics
Hematopoietic Stem Cell Transplantation
Humans
Infection - epidemiology
Infection - microbiology
Infection - virology
Infections
Major Article
Mammary gland diseases
Medical sciences
Middle Aged
Morbidity
Neutropenia
Progenitor cells
Transplantation
Transplantation, Autologous
Tumors
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Zusammenfassung:Autologous peripheral blood progenitor cell (PBPC) transplantation is increasingly employed in the outpatient setting, yet data on early complications following PBPC transplantation are scant. We evaluated 105 women with high-risk primary or metastatic breast cancer who were treated at a single institution during 1996–1997. The mean duration of neutropenia (absolute neutrophil count,
ISSN:1058-4838
1537-6591
DOI:10.1086/318715