Yes, MAM

Regulation of cell life and death by members of the BCL-2 family of proteins occurs at the mitochondria. Large portions of the mitochondria's outer membrane are found in tight approximation with the endoplasmic reticulum (ER), known as mitochondria-associated membranes (MAMs) or mitochondria-ER...

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Veröffentlicht in:Molecular & cellular oncology 2021-07, Vol.8 (4), p.1919473-1919473
Hauptverfasser: Means, Robert E., Katz, Samuel G.
Format: Artikel
Sprache:eng
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Zusammenfassung:Regulation of cell life and death by members of the BCL-2 family of proteins occurs at the mitochondria. Large portions of the mitochondria's outer membrane are found in tight approximation with the endoplasmic reticulum (ER), known as mitochondria-associated membranes (MAMs) or mitochondria-ER contact sites (MERCs). We recently reported that BOK is present within MAMs where it regulates Ca 2+ transfer from the ER to the mitochondria, appropriate MAM components and MERC structure, and apoptosis.
ISSN:2372-3556
2372-3556
DOI:10.1080/23723556.2021.1919473