The Beta-Adrenergic Receptor in Heart Failure

Although the role of the autonomic nervous system in the pathophysiology of heart failure has been studied for decades, only within the past few years have adrenergic receptors and their alterations occupied center stage. There is now considerable evidence linking such receptors to many of the pheno...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Hospital practice (1995) 1983-11, Vol.18 (11), p.103-125
Hauptverfasser:	Heinsimer, James A., Lefkowitz, Robert J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Agonists - therapeutic use Adrenergic beta-Antagonists - therapeutic use Animals Autonomic Nervous System - physiopathology Binding Sites - drug effects Catecholamines - metabolism Heart - physiopathology Heart Failure - drug therapy Heart Failure - physiopathology Humans Ligands Models, Biological Myocardium - metabolism Norepinephrine - physiology Protein Binding - drug effects Receptors, Adrenergic, alpha - analysis Receptors, Adrenergic, alpha - drug effects Receptors, Adrenergic, alpha - physiology Receptors, Adrenergic, beta - analysis Receptors, Adrenergic, beta - drug effects Receptors, Adrenergic, beta - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Although the role of the autonomic nervous system in the pathophysiology of heart failure has been studied for decades, only within the past few years have adrenergic receptors and their alterations occupied center stage. There is now considerable evidence linking such receptors to many of the phenomena of heart failure; recent work appears to have significant therapeutic implications.
ISSN:	2154-8331 8750-2836 2377-1003
DOI:	10.1080/21548331.1983.11702685