Transcription elongation

This review is focused on recent progress in understanding how Escherichia coli RNAP polymerase translocates along the DNA template and the factors that affect this movement. We discuss the fundamental aspects of RNAP translocation, template signals that influence forward or backward movement, and h...

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Veröffentlicht in:	Transcription 2017-05, Vol.8 (3), p.150-161
Hauptverfasser:	Mustaev, Arkady, Roberts, Jeffrey, Gottesman, Max
Format:	Artikel
Sprache:	eng
Schlagworte:	bacteriophage transcription factors DNA, Bacterial - metabolism DNA-Directed RNA Polymerases - genetics DNA-Directed RNA Polymerases - metabolism Escherichia coli - genetics Escherichia coli - metabolism Escherichia coli Proteins - genetics Escherichia coli Proteins - metabolism Gre A/B Point-of-View RNAP backtracking transcription elongation Transcription Elongation, Genetic - physiology transcription-coupled repair
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Beschreibung
Zusammenfassung:	This review is focused on recent progress in understanding how Escherichia coli RNAP polymerase translocates along the DNA template and the factors that affect this movement. We discuss the fundamental aspects of RNAP translocation, template signals that influence forward or backward movement, and host or phage factors that modulate translocation.
ISSN:	2154-1264 2154-1272
DOI:	10.1080/21541264.2017.1289294