The HMGA1-pseudogene7 shows oncogenic activity in vivo

The HMGA1-pseudogene7 shows oncogenic activity in vivo

We have recently reported that transgenic mice overexpressing the HMGA1-pseudogene7 develop hematological neoplasia marked by monoclonal B-cell populations, and diagnosed as Diffuse Large B-cell Lymphoma. These findings prove the HMGA1-pseudogene7 oncogenic role in vivo.

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Veröffentlicht in:Cell cycle (Georgetown, Tex.) Tex.), 2020-11, Vol.19 (22), p.2955-2959
Hauptverfasser: De Martino, Marco, Esposito, Francesco, Fusco, Alfredo
Format: Artikel
Sprache:eng
Schlagworte:
ceRNA
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HMGA1 pseudogenes
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transgenic mouse models
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Zusammenfassung:We have recently reported that transgenic mice overexpressing the HMGA1-pseudogene7 develop hematological neoplasia marked by monoclonal B-cell populations, and diagnosed as Diffuse Large B-cell Lymphoma. These findings prove the HMGA1-pseudogene7 oncogenic role in vivo.
ISSN:1538-4101
1551-4005
DOI:10.1080/15384101.2020.1829825