Novel Types of Spin Labelled Nucleoside Analogues

Novel Types of Spin Labelled Nucleoside Analogues

A variety of modified nucleosides or dinucleosides bearing one of the following functions have been prepared: N-hydroxyureas, N-hydroxyamines, N-hydroxycarbamates, α-(N-hydroxyamino)phosphonates. Upon oxidation, these compounds afford the corresponding aminoxyl free radicals which have been studied...

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Veröffentlicht in:Nucleosides & nucleotides 1999-04, Vol.18 (4-5), p.649-650
Hauptverfasser: Tronchet, J. M. J., Zsély, M., Grand, E., Laroze, N., Iznaden, M., Sollini, M., Geoffroy, M.
Format: Artikel
Sprache:eng
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Zusammenfassung:A variety of modified nucleosides or dinucleosides bearing one of the following functions have been prepared: N-hydroxyureas, N-hydroxyamines, N-hydroxycarbamates, α-(N-hydroxyamino)phosphonates. Upon oxidation, these compounds afford the corresponding aminoxyl free radicals which have been studied by EPR spectroscopy. Some of these compounds exhibited antiviral properties.
ISSN:0732-8311
DOI:10.1080/15257779908041528