Synthesis of 3′-4′-α-Propylene-2′-3′-dideoxynucleosides
In order to obtain a high degree of rigidity within the sugar moiety of nucleosides, some bicyclic pyrimidine nucleoside analogues where synthesized starting from cyclopentanone. The C-4′-substituent is fused to the C-3′-position via a propylene to give a [3.3.0]-bicyclic ring system.
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Veröffentlicht in: | Nucleosides & nucleotides 1995-05, Vol.14 (3-5), p.279-282 |
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Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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Zusammenfassung: | In order to obtain a high degree of rigidity within the sugar moiety of nucleosides, some bicyclic pyrimidine nucleoside analogues where synthesized starting from cyclopentanone. The C-4′-substituent is fused to the C-3′-position via a propylene to give a [3.3.0]-bicyclic ring system. |
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ISSN: | 0732-8311 1525-7770 |
DOI: | 10.1080/15257779508012361 |