Evaluation of paradoxical effect of small dose ketamine as adjuvant in deep sedation for endoscopy patients
This study tested the hypothesis that use of ketamine as an adjuvant to propofol in the induction of deep sedation for endoscopy patients could lead, paradoxically, to faster emergence. We conducted a single-center, prospective randomized controlled study on 154 adult ASA I or II patients, adm...
Gespeichert in:
| Veröffentlicht in: | Egyptian journal of anaesthesia 2023-12, Vol.39 (1), p.128-133 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | This study tested the hypothesis that use of ketamine as an adjuvant to propofol in the induction of deep sedation for endoscopy patients could lead, paradoxically, to faster emergence.
We conducted a single-center, prospective randomized controlled study on 154 adult ASA I or II patients, admitted for gastrointestinal endoscopies. Patients were sedated with 25 µg fentanyl and 1 mg/kg propofol bolus over 30 s. Patients were divided into two groups: Group P (n = 77), sedated with propofol only, and Group PK (n = 77), who received additionally a single dose of ketamine (0.1 mg/kg) at induction. If the patient moved or Ramsay Sedation Score (RSS) regressed to |
|---|---|
| ISSN: | 1110-1849 1687-1804 1110-1849 |
| DOI: | 10.1080/11101849.2023.2166653 |