NO Synthesis in Human Saliva
Human saliva contains nitrate that is converted into nitrite by the activity of facultative, anaerobic bacteria of the oral cavity. Nitrite can be reduced to NO in the acidic gastric milieu; some NO may also form in the mouth at acidic pH values. In this paper, we show that bacteria ( S. salivarius,...
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| Veröffentlicht in: | Free radical research 2003, Vol.37 (1), p.29-31 |
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| container_title | Free radical research |
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| creator | Palmerini, C.A. Palombari, R. Perito, S. Arienti, G. |
| description | Human saliva contains nitrate that is converted into nitrite by the activity of facultative, anaerobic bacteria of the oral cavity. Nitrite can be reduced to NO in the acidic gastric milieu; some NO may also form in the mouth at acidic pH values. In this paper, we show that bacteria ( S. salivarius, S. mitis and S. bovis ) isolated from saliva, may contribute to NO production in human saliva. NO formation by bacteria occurs at neutral pH values and may contribute to the antibacterial activity of saliva. |
| doi_str_mv | 10.1080/1071576021000028398 |
| format | Article |
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Nitrite can be reduced to NO in the acidic gastric milieu; some NO may also form in the mouth at acidic pH values. In this paper, we show that bacteria ( S. salivarius, S. mitis and S. bovis ) isolated from saliva, may contribute to NO production in human saliva. NO formation by bacteria occurs at neutral pH values and may contribute to the antibacterial activity of saliva.</description><identifier>ISSN: 1071-5762</identifier><identifier>EISSN: 1029-2470</identifier><identifier>DOI: 10.1080/1071576021000028398</identifier><identifier>PMID: 12653214</identifier><language>eng</language><publisher>England: Informa UK Ltd</publisher><subject>Adult ; Amperometric Sensor ; Anti-Bacterial Agents - metabolism ; Bacteria ; Female ; Humans ; Hydrogen-Ion Concentration ; In Vitro Techniques ; Nitric Oxide - biosynthesis ; Nitrite ; Nitrites - metabolism ; Saliva ; Saliva - metabolism ; Saliva - microbiology ; Streptococcus - isolation & purification ; Streptococcus - metabolism ; Streptococcus bovis - isolation & purification ; Streptococcus bovis - metabolism ; Streptococcus mitis - isolation & purification ; Streptococcus mitis - metabolism ; Streptococcus Salivarius</subject><ispartof>Free radical research, 2003, Vol.37 (1), p.29-31</ispartof><rights>2003 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2003</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c410t-7f55b31383274ae47710ee2f7cf98220d27fd7546f720ae59ac2b0fbafeea583</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1080/1071576021000028398$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1080/1071576021000028398$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>315,782,786,4028,27932,27933,27934,59656,60445,61230,61411</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12653214$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Palmerini, C.A.</creatorcontrib><creatorcontrib>Palombari, R.</creatorcontrib><creatorcontrib>Perito, S.</creatorcontrib><creatorcontrib>Arienti, G.</creatorcontrib><title>NO Synthesis in Human Saliva</title><title>Free radical research</title><addtitle>Free Radic Res</addtitle><description>Human saliva contains nitrate that is converted into nitrite by the activity of facultative, anaerobic bacteria of the oral cavity. 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NO formation by bacteria occurs at neutral pH values and may contribute to the antibacterial activity of saliva.</description><subject>Adult</subject><subject>Amperometric Sensor</subject><subject>Anti-Bacterial Agents - metabolism</subject><subject>Bacteria</subject><subject>Female</subject><subject>Humans</subject><subject>Hydrogen-Ion Concentration</subject><subject>In Vitro Techniques</subject><subject>Nitric Oxide - biosynthesis</subject><subject>Nitrite</subject><subject>Nitrites - metabolism</subject><subject>Saliva</subject><subject>Saliva - metabolism</subject><subject>Saliva - microbiology</subject><subject>Streptococcus - isolation & purification</subject><subject>Streptococcus - metabolism</subject><subject>Streptococcus bovis - isolation & purification</subject><subject>Streptococcus bovis - metabolism</subject><subject>Streptococcus mitis - isolation & purification</subject><subject>Streptococcus mitis - metabolism</subject><subject>Streptococcus Salivarius</subject><issn>1071-5762</issn><issn>1029-2470</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1Lw0AQhhdRbK3-AkV68had2c1mk4OCFLVCsYf2vkySXZqSj7qbKP33prQggnQuM4dn3hkexq4R7hFieEBQKFUEHKEvHoskPmFDBJ4EPFRwupsVBj3CB-zC-zUAilCqczZAHknBMRyym4_5eLGt25XxhR8X9XjaVVSPF1QWX3TJziyV3lwd-ogtX1-Wk2kwm7-9T55nQRYitIGyUqYCRSy4CsmESiEYw63KbBJzDjlXNlcyjKziQEYmlPEUbErWGJKxGLG7fezGNZ-d8a2uCp-ZsqTaNJ3XSiDGSRT1oNiDmWu8d8bqjSsqcluNoHdO9D9O-q3bQ3yXVib_3TlI6IGnPVDUtnEVfTeuzHVL27Jx1lGdFV6L4xce_wSsDJXtKiNn9LrpXN27O_rhDw6Tf64</recordid><startdate>2003</startdate><enddate>2003</enddate><creator>Palmerini, C.A.</creator><creator>Palombari, R.</creator><creator>Perito, S.</creator><creator>Arienti, G.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2003</creationdate><title>NO Synthesis in Human Saliva</title><author>Palmerini, C.A. ; Palombari, R. ; Perito, S. ; Arienti, G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c410t-7f55b31383274ae47710ee2f7cf98220d27fd7546f720ae59ac2b0fbafeea583</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Adult</topic><topic>Amperometric Sensor</topic><topic>Anti-Bacterial Agents - metabolism</topic><topic>Bacteria</topic><topic>Female</topic><topic>Humans</topic><topic>Hydrogen-Ion Concentration</topic><topic>In Vitro Techniques</topic><topic>Nitric Oxide - biosynthesis</topic><topic>Nitrite</topic><topic>Nitrites - metabolism</topic><topic>Saliva</topic><topic>Saliva - metabolism</topic><topic>Saliva - microbiology</topic><topic>Streptococcus - isolation & purification</topic><topic>Streptococcus - metabolism</topic><topic>Streptococcus bovis - isolation & purification</topic><topic>Streptococcus bovis - metabolism</topic><topic>Streptococcus mitis - isolation & purification</topic><topic>Streptococcus mitis - metabolism</topic><topic>Streptococcus Salivarius</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Palmerini, C.A.</creatorcontrib><creatorcontrib>Palombari, R.</creatorcontrib><creatorcontrib>Perito, S.</creatorcontrib><creatorcontrib>Arienti, G.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Free radical research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Palmerini, C.A.</au><au>Palombari, R.</au><au>Perito, S.</au><au>Arienti, G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>NO Synthesis in Human Saliva</atitle><jtitle>Free radical research</jtitle><addtitle>Free Radic Res</addtitle><date>2003</date><risdate>2003</risdate><volume>37</volume><issue>1</issue><spage>29</spage><epage>31</epage><pages>29-31</pages><issn>1071-5762</issn><eissn>1029-2470</eissn><abstract>Human saliva contains nitrate that is converted into nitrite by the activity of facultative, anaerobic bacteria of the oral cavity. 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| ispartof | Free radical research, 2003, Vol.37 (1), p.29-31 |
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| source | MEDLINE; Taylor & Francis:Master (3349 titles) |
| subjects | Adult Amperometric Sensor Anti-Bacterial Agents - metabolism Bacteria Female Humans Hydrogen-Ion Concentration In Vitro Techniques Nitric Oxide - biosynthesis Nitrite Nitrites - metabolism Saliva Saliva - metabolism Saliva - microbiology Streptococcus - isolation & purification Streptococcus - metabolism Streptococcus bovis - isolation & purification Streptococcus bovis - metabolism Streptococcus mitis - isolation & purification Streptococcus mitis - metabolism Streptococcus Salivarius |
| title | NO Synthesis in Human Saliva |
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