An Efficient Method for the Synthesis of Methyl 12α-Hydroxy-Isocopal-13(14)-En-15-Oate, a Key Precursor to a Variety of Sesterterpene Marine Sponge Metabolites

An efficient method for the synthesis of methyl 12α-hydroxy-isocopal-13(14)en-15-oate (2), a key intermediate to a variety of sesterterpene marine sponge metabolites, is described.

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Veröffentlicht in:Natural product letters 1998-09, Vol.12 (2), p.139-143
Hauptverfasser: Nakano, Tatsuhiko, Hidalgo, Rosabel Torrellas, Martin, Alfonso, Medina, Jose D., Maillo, Maria Aracelis
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container_end_page 143
container_issue 2
container_start_page 139
container_title Natural product letters
container_volume 12
creator Nakano, Tatsuhiko
Hidalgo, Rosabel Torrellas
Martin, Alfonso
Medina, Jose D.
Maillo, Maria Aracelis
description An efficient method for the synthesis of methyl 12α-hydroxy-isocopal-13(14)en-15-oate (2), a key intermediate to a variety of sesterterpene marine sponge metabolites, is described.
doi_str_mv 10.1080/10575639808048283
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source Taylor & Francis Journals Complete
subjects Marine sponge metabolites
precursor
sesterterpenes
synthesis
title An Efficient Method for the Synthesis of Methyl 12α-Hydroxy-Isocopal-13(14)-En-15-Oate, a Key Precursor to a Variety of Sesterterpene Marine Sponge Metabolites
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