An Efficient Method for the Synthesis of Methyl 12α-Hydroxy-Isocopal-13(14)-En-15-Oate, a Key Precursor to a Variety of Sesterterpene Marine Sponge Metabolites

An Efficient Method for the Synthesis of Methyl 12α-Hydroxy-Isocopal-13(14)-En-15-Oate, a Key Precursor to a Variety of Sesterterpene Marine Sponge Metabolites

An efficient method for the synthesis of methyl 12α-hydroxy-isocopal-13(14)en-15-oate (2), a key intermediate to a variety of sesterterpene marine sponge metabolites, is described.

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Bibliographische Detailangaben
Veröffentlicht in:Natural product letters 1998-09, Vol.12 (2), p.139-143
Hauptverfasser: Nakano, Tatsuhiko, Hidalgo, Rosabel Torrellas, Martin, Alfonso, Medina, Jose D., Maillo, Maria Aracelis
Format: Artikel
Sprache:eng
Schlagworte:
Marine sponge metabolites
precursor
sesterterpenes
synthesis
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Beschreibung
Zusammenfassung:An efficient method for the synthesis of methyl 12α-hydroxy-isocopal-13(14)en-15-oate (2), a key intermediate to a variety of sesterterpene marine sponge metabolites, is described.
ISSN:1057-5634
DOI:10.1080/10575639808048283