CD4+ T lymphocyte counts after autologous transplantation in multiple myeloma: A retrospective study

The risk for opportunistic infections is correlated with low CD4+ T lymphocyte counts in patients with HIV. We performed a retrospective analysis in 54 patients with multiple myeloma undergoing high-dose melphalan chemotherapy + autologous peripheral blood stem cell transplantation to better define...

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Veröffentlicht in:	Leukemia & lymphoma 2007-01, Vol.48 (3), p.506-512
Hauptverfasser:	Gorschlüter, Marcus, Glasmacher, Axel, Sarazin, Susann, Hackbarth, Frank, Hoebert, Eckfried, Orlopp, Katjana, Schmidt-Wolf, Ingo G. H., Mey, Ulrich
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic Agents, Alkylating - administration & dosage autologous stem cell transplantation Biomarkers - analysis CD4 Lymphocyte Count CD4+ T lymphocytes CD4-Positive T-Lymphocytes - immunology Female Humans infections Male Melphalan - administration & dosage Middle Aged multiple myeloma Multiple Myeloma - immunology Multiple Myeloma - therapy Peripheral Blood Stem Cell Transplantation Prognosis Retrospective Studies Survival Rate Transplantation, Autologous
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Zusammenfassung:	The risk for opportunistic infections is correlated with low CD4+ T lymphocyte counts in patients with HIV. We performed a retrospective analysis in 54 patients with multiple myeloma undergoing high-dose melphalan chemotherapy + autologous peripheral blood stem cell transplantation to better define the value of routine control of CD4+ T lymphocyte counts in this important patient group. In 61% of our patients, CD4+ T lymphocyte counts after recovery from neutropenia were
ISSN:	1042-8194 1029-2403
DOI:	10.1080/10428190601094347