biological activities of 20 nature identical essential oil constituents

Twenty nature identical essential oil constituents from seven structural groups were tested for antimalarial, antimicrobial, antioxidant and toxicity properties. The compounds displayed antimalarial activity (IC50 values ranging from 0.9 to 1528.8 micromolar) with varying toxicity (IC50 values rangi...

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Veröffentlicht in:	The Journal of essential oil research 2006, Vol.18 (sup1), p.129-133
Hauptverfasser:	Van Zyl, R.L, Seatlholo, S.T, Van Vuuren, S.F, Viljoen, A.M
Format:	Artikel
Sprache:	eng
Schlagworte:	(+)-carvone (+)-limonene (+)-α-pinene (+)-β-pinene (-)-citronellal (-)-fenchone (-)-menthone (-)-pulegone (-)-α-bisabolol (E-& Z-)-(±)-nerolidol (±)-linalool (±)-α+β-thujone 1,8-cineole antimalarial activity antimalarials antimicrobial activity antimicrobial properties antioxidant activity aromatic plant carvacrol chemical composition essential oil crops essential oils eugenol free radicals geraniol linalyl acetate medicinal plants minimum inhibitory concentration monoterpenoids Nature identical essential oil constituent p-cymene plant extracts toxicity traditional medicine trans-geranyl acetate volatile compounds γ-terpinene
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Beschreibung
Zusammenfassung:	Twenty nature identical essential oil constituents from seven structural groups were tested for antimalarial, antimicrobial, antioxidant and toxicity properties. The compounds displayed antimalarial activity (IC50 values ranging from 0.9 to 1528.8 micromolar) with varying toxicity (IC50 values ranging from 5.5 to 1358.4 micromolar). The data indicates that (-)-pulegone, (E- & Z-)-(+/-)-nerolidol, linalyl acetate and (+)-alpha-pinene have the most potent antimalaial activity. Carvacrol (MIC values ranging from
ISSN:	1041-2905 2163-8152
DOI:	10.1080/10412905.2006.12067134