Silicone gel breast implants and connective tissue disease: A comprehensive review
Silicone breast implants have been in use for breast reconstruction and breast augmentation for a long time. In the late 80's anecdotal reports describing a possible association between silicone-gel filled breast implants, and autoimmune diseases was accumulating. Due to the growing concern abo...
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| Veröffentlicht in: | Autoimmunity (Chur, Switzerland) Switzerland), 2003-06, Vol.36 (4), p.193-197 |
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| container_title | Autoimmunity (Chur, Switzerland) |
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| creator | BAR-MEIR, Eran EHERENFELD, Michael SHOENFELD, Yehuda |
| description | Silicone breast implants have been in use for breast reconstruction and breast augmentation for a long time. In the late 80's anecdotal reports describing a possible association between silicone-gel filled breast implants, and autoimmune diseases was accumulating. Due to the growing concern about the safety of silicone-gel implants, the Food and Drug administration (FDA) restricted their use to participants in controlled clinical trials, including women having reconstructive surgery. However, in recent years, large meta-analyses were unable to establish an association between silicone-gel breast implants and autoimmune disease. We review the current literature, emphasizing the most important epidemiologic studies. |
| doi_str_mv | 10.1080/08916931000148818 |
| format | Article |
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In the late 80's anecdotal reports describing a possible association between silicone-gel filled breast implants, and autoimmune diseases was accumulating. Due to the growing concern about the safety of silicone-gel implants, the Food and Drug administration (FDA) restricted their use to participants in controlled clinical trials, including women having reconstructive surgery. However, in recent years, large meta-analyses were unable to establish an association between silicone-gel breast implants and autoimmune disease. We review the current literature, emphasizing the most important epidemiologic studies.</description><identifier>ISSN: 0891-6934</identifier><identifier>EISSN: 1607-842X</identifier><identifier>DOI: 10.1080/08916931000148818</identifier><identifier>PMID: 14563011</identifier><language>eng</language><publisher>Abingdon: Taylor and Francis</publisher><subject>Autoimmune Diseases - etiology ; Biological and medical sciences ; Breast Implants - adverse effects ; Connective Tissue Diseases - etiology ; Female ; Humans ; Medical sciences ; Risk Assessment - legislation & jurisprudence ; Risk Assessment - methods ; Silicone Gels - adverse effects ; Surgery (general aspects). Transplantations, organ and tissue grafts. 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In the late 80's anecdotal reports describing a possible association between silicone-gel filled breast implants, and autoimmune diseases was accumulating. Due to the growing concern about the safety of silicone-gel implants, the Food and Drug administration (FDA) restricted their use to participants in controlled clinical trials, including women having reconstructive surgery. However, in recent years, large meta-analyses were unable to establish an association between silicone-gel breast implants and autoimmune disease. We review the current literature, emphasizing the most important epidemiologic studies.</description><subject>Autoimmune Diseases - etiology</subject><subject>Biological and medical sciences</subject><subject>Breast Implants - adverse effects</subject><subject>Connective Tissue Diseases - etiology</subject><subject>Female</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Risk Assessment - legislation & jurisprudence</subject><subject>Risk Assessment - methods</subject><subject>Silicone Gels - adverse effects</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the genital tract and mammary gland</subject><subject>United States</subject><subject>United States Food and Drug Administration</subject><issn>0891-6934</issn><issn>1607-842X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkEtLxDAURoMozjj6A9xINi6rN02apO6GwRcMCD7AXUmTW420nZJ0Rvz3ZnBAwdVdnHPu4iPklMEFAw2XoEsmS84AgAmtmd4jUyZBZVrkr_tkuuVZEsSEHMX4kbRcSXFIJkwUkgNjU_L45FtvVz3SN2xpHdDEkfpuaE0_Rmp6RxPs0Y5-g3T0Ma6ROh-Thld0nmA3BHzHPm55wI3Hz2Ny0Jg24snuzsjLzfXz4i5bPtzeL-bLzHJRjJkutdPCsjovodG5US5vTF3L3LjGiYJZQKtAqVpqqQWXvADjWCElAueoFZ8R9vPXhlWMAZtqCL4z4atiUG33qf7tk5qzn2ZY1x2632I3SBLOd4KJ1rRNML318Y9XKsh1yb8BXlhtFQ</recordid><startdate>200306</startdate><enddate>200306</enddate><creator>BAR-MEIR, Eran</creator><creator>EHERENFELD, Michael</creator><creator>SHOENFELD, Yehuda</creator><general>Taylor and Francis</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>200306</creationdate><title>Silicone gel breast implants and connective tissue disease: A comprehensive review</title><author>BAR-MEIR, Eran ; EHERENFELD, Michael ; SHOENFELD, Yehuda</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c345t-898d84c1b290f82a7d2fabb62adfd451c0ec7077b6868436350ad1566e033e873</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Autoimmune Diseases - etiology</topic><topic>Biological and medical sciences</topic><topic>Breast Implants - adverse effects</topic><topic>Connective Tissue Diseases - etiology</topic><topic>Female</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Risk Assessment - legislation & jurisprudence</topic><topic>Risk Assessment - methods</topic><topic>Silicone Gels - adverse effects</topic><topic>Surgery (general aspects). 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Graft diseases</topic><topic>Surgery of the genital tract and mammary gland</topic><topic>United States</topic><topic>United States Food and Drug Administration</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BAR-MEIR, Eran</creatorcontrib><creatorcontrib>EHERENFELD, Michael</creatorcontrib><creatorcontrib>SHOENFELD, Yehuda</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Autoimmunity (Chur, Switzerland)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>BAR-MEIR, Eran</au><au>EHERENFELD, Michael</au><au>SHOENFELD, Yehuda</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Silicone gel breast implants and connective tissue disease: A comprehensive review</atitle><jtitle>Autoimmunity (Chur, Switzerland)</jtitle><addtitle>Autoimmunity</addtitle><date>2003-06</date><risdate>2003</risdate><volume>36</volume><issue>4</issue><spage>193</spage><epage>197</epage><pages>193-197</pages><issn>0891-6934</issn><eissn>1607-842X</eissn><abstract>Silicone breast implants have been in use for breast reconstruction and breast augmentation for a long time. In the late 80's anecdotal reports describing a possible association between silicone-gel filled breast implants, and autoimmune diseases was accumulating. Due to the growing concern about the safety of silicone-gel implants, the Food and Drug administration (FDA) restricted their use to participants in controlled clinical trials, including women having reconstructive surgery. However, in recent years, large meta-analyses were unable to establish an association between silicone-gel breast implants and autoimmune disease. We review the current literature, emphasizing the most important epidemiologic studies.</abstract><cop>Abingdon</cop><pub>Taylor and Francis</pub><pmid>14563011</pmid><doi>10.1080/08916931000148818</doi><tpages>5</tpages></addata></record> |
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| ispartof | Autoimmunity (Chur, Switzerland), 2003-06, Vol.36 (4), p.193-197 |
| issn | 0891-6934 1607-842X |
| language | eng |
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| source | MEDLINE; Access via Taylor & Francis |
| subjects | Autoimmune Diseases - etiology Biological and medical sciences Breast Implants - adverse effects Connective Tissue Diseases - etiology Female Humans Medical sciences Risk Assessment - legislation & jurisprudence Risk Assessment - methods Silicone Gels - adverse effects Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the genital tract and mammary gland United States United States Food and Drug Administration |
| title | Silicone gel breast implants and connective tissue disease: A comprehensive review |
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