Study of intercurrent infection pattern in hepatitis C seropositive renal transplant recipients, relationship with T-cell function

Background: We assessed the effect of hepatitis C seropositivity on the percentage of various T-cells in living donor renal transplant recipients (LDRTRs) and their association with intercurrent infections post renal transplantation (post-Tx). Methods: One hundred and thirty-three matching LDRTRs [A (seronegative) (68 patients) and B (seropositive) (65 patients) by ELISA] were studied prospectively 10 days, 6 months and 12 months post-Tx for intercurrent infections, acute rejection and T-cell% by flow cytometry. Results: CD4 + , CD8 + , CD4/CD8 were significantly higher 10 days post-Tx in Group B compared to Group A, p