MICROENCAPSULATION BY SPRAY DRYING
Spray drying technique has been widely used for drying heat-sensitive foods, pharmaceuticals, and other substances, because of the solvent rapid evaporation from the droplets, Although most often considered a dehydration process, spray drying can also be used as an encapsulation method when it entra...
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Veröffentlicht in: | Drying technology 1998-01, Vol.16 (6), p.1195-1236 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Spray drying technique has been widely used for drying heat-sensitive foods, pharmaceuticals, and other substances, because of the solvent rapid evaporation from the droplets, Although most often considered a dehydration process, spray drying can also be used as an encapsulation method when it entraps 'active' material within a protective matrix, which is essentially inert to the material being encapsulated. Compared to the other conventional microencapsulation techniques, it offers the attractive advantage of producing microcapsules in a relatively simple continuous processing operation. This chapter will present a brief overview of the main considerations involved in the application of spray drying for microencapsulation, with a special emphasis given to microencapsulation of volatile materials. The potential use of spray drying microencapsulation for pharmaceutical applications, particularly the preparation of microparticulate drug delivery systems, will also be discussed |
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ISSN: | 0737-3937 1532-2300 |
DOI: | 10.1080/07373939808917460 |