Preparation of Oligonucleotides Containing Non-Natural Base Analogs
The preparation of oligonucleotides containing 5-amino-2′-deoxyuridine, 5-Nacetamido- 2′-deoxyuridine, 5-aza-2′-deoxycytidine and N 2 -substituted guanosine derivatives is described. In each case selection of the appropriate protective group, synthesis and deprotection conditions is discussed.
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Veröffentlicht in: | Nucleosides & nucleotides 1997-05, Vol.16 (5-6), p.697-702 |
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Hauptverfasser: | , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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Zusammenfassung: | The preparation of oligonucleotides containing 5-amino-2′-deoxyuridine, 5-Nacetamido- 2′-deoxyuridine, 5-aza-2′-deoxycytidine and N
2
-substituted guanosine derivatives is described. In each case selection of the appropriate protective group, synthesis and deprotection conditions is discussed. |
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ISSN: | 0732-8311 |
DOI: | 10.1080/07328319708002936 |