Incorporation of 5′-N-BOC-2′, 5′-Dideoxynucleoside-3′-O-Phosphoramidites Into Oligonucleotides by Automated Synthesis

An efficient method for synthesizing 5′-Boc-5′-amino-2′, 5′- dideoxynucleoside phosphoramidites and conditions for their incorporation in solid-phase oligonucleotide synthesis are presented.

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Veröffentlicht in:	Nucleosides & nucleotides 1997-10, Vol.16 (10-11), p.1821-1836
Hauptverfasser:	James, Kenneth D., Kiedrowski, Guenter von, Ellington, Andrew D.
Format:	Artikel
Sprache:	eng
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creator	James, Kenneth D. Kiedrowski, Guenter von Ellington, Andrew D.
description	An efficient method for synthesizing 5′-Boc-5′-amino-2′, 5′- dideoxynucleoside phosphoramidites and conditions for their incorporation in solid-phase oligonucleotide synthesis are presented.
doi_str_mv	10.1080/07328319708002536
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title	Incorporation of 5′-N-BOC-2′, 5′-Dideoxynucleoside-3′-O-Phosphoramidites Into Oligonucleotides by Automated Synthesis
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