The Preparation and Utility of 5-β-D-Ribofuranosyl-(2H)-Tetrazole as a Key Synthon for C-Nucleoside Chemistry

The Preparation and Utility of 5-β-D-Ribofuranosyl-(2H)-Tetrazole as a Key Synthon for C-Nucleoside Chemistry

A synthesis of 5-β-D-ribofuranosyl-2H-tetrazole (1) 5-β-D.-ribofuranosyl-oxadiazoles, diethyl-δ2 -pyrazoline-4,5-dicarboxylate and diethylpyrazole-4,5-dicarboxylate derivatives is described. Ring transformations of1, has been investigated in an effort to establish the stability of this synthon for f...

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Veröffentlicht in:Nucleosides & nucleotides 1987-01, Vol.6 (1-2), p.365-368
Hauptverfasser: Kobe, Joze, Prhavc, Marija, Hohnjec, Marijan, Townsend, Leroy B.
Format: Artikel
Sprache:eng
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Zusammenfassung:A synthesis of 5-β-D-ribofuranosyl-2H-tetrazole (1) 5-β-D.-ribofuranosyl-oxadiazoles, diethyl-δ2 -pyrazoline-4,5-dicarboxylate and diethylpyrazole-4,5-dicarboxylate derivatives is described. Ring transformations of1, has been investigated in an effort to establish the stability of this synthon for further use in dipolar cycloaddition reactions.
ISSN:0732-8311
2332-3892
DOI:10.1080/07328318708056222