Synthesis and Properties of N-Organosililmethyllactams

The heterofunctional condensation of lactams with chloromethyl derivatives of organosilanes in the presence of catalyst-acceptor of anhydrous K 2 CO 3 or Na 2 CO 3 has been investigated. The hydrolytic stability of N-dialkyl(aryl)silylmethyllactams in neutral, acid and alkaline media has been studied. The biological activity of synthesized silicon-containing lactams has been investigated. The hydrolytic poly-condensation of N-(methyldimethoxysilylmethyl) lactams in the presence of a catalytic quantity of concentrated hydrochloric acid at room temperature has been conducted.