A Facile Route to Quinazolin-4(3H)-ones Functionalised at the 2-Position
Treatment of 2-methoxyacetamidobenzonitriles or 2-chloroacetamidobenzonitrile with UHP and K 2 CO 3 provides a convenient route to 2-methoxymethyl-or 2-chloromethylquinazolin-4(3H)-ones. In addition, demethylation of 2-methoxymethylquinazolin-4(3H)-ones with 48% HBr gives 2-hydroxymethylquinazolin-4...
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| Veröffentlicht in: | Synthetic communications 1998-12, Vol.28 (24), p.4547-4559 |
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| container_issue | 24 |
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| container_title | Synthetic communications |
| container_volume | 28 |
| creator | Bavetsias, V. |
| description | Treatment of 2-methoxyacetamidobenzonitriles or 2-chloroacetamidobenzonitrile with UHP and K
2
CO
3
provides a convenient route to 2-methoxymethyl-or 2-chloromethylquinazolin-4(3H)-ones. In addition, demethylation of 2-methoxymethylquinazolin-4(3H)-ones with 48% HBr gives 2-hydroxymethylquinazolin-4(3H)-ones. |
| doi_str_mv | 10.1080/00397919808004519 |
| format | Article |
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CO
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CO
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2
CO
3
provides a convenient route to 2-methoxymethyl-or 2-chloromethylquinazolin-4(3H)-ones. In addition, demethylation of 2-methoxymethylquinazolin-4(3H)-ones with 48% HBr gives 2-hydroxymethylquinazolin-4(3H)-ones.</abstract><pub>Taylor & Francis Group</pub><doi>10.1080/00397919808004519</doi><tpages>13</tpages></addata></record> |
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| ispartof | Synthetic communications, 1998-12, Vol.28 (24), p.4547-4559 |
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| language | eng |
| recordid | cdi_crossref_primary_10_1080_00397919808004519 |
| source | Access via Taylor & Francis |
| title | A Facile Route to Quinazolin-4(3H)-ones Functionalised at the 2-Position |
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