Triflate Induced C-N Coupling of Sugars with Heterocyclic Bases: Synthesis of a New Class of Compounds

A new class of pharmacologically interesting compounds has been synthesized through a novel S N 2 displacement of trifluoromethanesulfonyloxy group in protected sugar (1) with a variety of secondary heterocyclic cases (2-6). The reaction pathway also provides a possible route to alklodial N-glycosid...

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Veröffentlicht in:Synthetic communications 1988-04, Vol.18 (5), p.501-505
Hauptverfasser: Ahmed, Zaheer, Kazmi, Syed Najam-ul-Hussain, Ahmad, Syed Salman, Khan, Abdul Qasim, Malik, Abdul
Format: Artikel
Sprache:eng
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Zusammenfassung:A new class of pharmacologically interesting compounds has been synthesized through a novel S N 2 displacement of trifluoromethanesulfonyloxy group in protected sugar (1) with a variety of secondary heterocyclic cases (2-6). The reaction pathway also provides a possible route to alklodial N-glycosides.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397918808060743