An Efficient Synthetic Sequence for Sondheimer's Onocerin Intermediate. A Clarification

The purpose of this communication is to describe an efficient, low-cost, large-scale preparation of decalone 2 which was first prepared by Sondheimer and Elad in eleven steps from the Wieland-Mischer ketone 1 . Later, this route (1←2) was modified by several groups but all these procedures have suff...

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Veröffentlicht in:Synthetic communications 1985-03, Vol.15 (4), p.341-354
Hauptverfasser: Kokosi, Joseph, Schmidt, Cirill
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
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Zusammenfassung:The purpose of this communication is to describe an efficient, low-cost, large-scale preparation of decalone 2 which was first prepared by Sondheimer and Elad in eleven steps from the Wieland-Mischer ketone 1 . Later, this route (1←2) was modified by several groups but all these procedures have suffered from the dis- advantage that the catalytic hydrogenation of the double bond present in the various intermediates was not stereospecific.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397918508063809