Synthesis of Azetidin-2-Ones from Imines and Acids Using Trichloroacetonitrile-Triphenylphosphine Reagent

Synthesis of Azetidin-2-Ones from Imines and Acids Using Trichloroacetonitrile-Triphenylphosphine Reagent

A one step synthesis of azetidin-2-ones (3a-j) has been described by the reaction of imines (1) with acids (2) in presence of trichloroacetonitrile, triphenylphosphine and triethylamine.

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Veröffentlicht in:Synthetic communications 2000-11, Vol.30 (22), p.4177-4182
Hauptverfasser: Govande, Vidyesh V., Arun, M., Deshmukh, A. R. A. S., Bhawal, B. M.
Format: Artikel
Sprache:eng
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Zusammenfassung:A one step synthesis of azetidin-2-ones (3a-j) has been described by the reaction of imines (1) with acids (2) in presence of trichloroacetonitrile, triphenylphosphine and triethylamine.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397910008087035