Effect of Circulating Peptide YY on Gallbladder Emptying in Humans

Background: To further establish its role in the ileal brake mechanism, we determined the effect of the distal gut hormone peptide YY (PYY) on gallbladder motility and plasma gut hormones during the cephalic phase of meal stimulation. Methods: Eight healthy volunteers were studied in a randomized cr...

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Veröffentlicht in:	Scandinavian journal of gastroenterology 2001, Vol.36 (10), p.1086-1091
Hauptverfasser:	HOENTJEN, F, HOPMAN, W. P. M, JANSEN, J. B. M. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Celiac Disease - blood Celiac Disease - physiopathology Cephalic Phase Cholecystokinin Pancreatic Polypeptide Sham Feeding Cholecystokinin - blood Cross-Over Studies Fasting Female Food Fundamental and applied biological sciences. Psychology Gallbladder Emptying - drug effects Gallbladder Emptying - physiology Humans Injections, Intravenous Liver. Bile. Biliary tracts Male Middle Aged Pancreatic Polypeptide - blood Peptide YY - administration & dosage Peptide YY - blood Peptide YY - pharmacology Vagus Nerve - physiology Vertebrates: digestive system
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Beschreibung
Zusammenfassung:	Background: To further establish its role in the ileal brake mechanism, we determined the effect of the distal gut hormone peptide YY (PYY) on gallbladder motility and plasma gut hormones during the cephalic phase of meal stimulation. Methods: Eight healthy volunteers were studied in a randomized crossover design, with or without intravenous infusion of a physiological dose of PYY. On each occasion, subjects underwent modified sham feeding followed by real feeding. Results:
ISSN:	0036-5521 1502-7708
DOI:	10.1080/003655201750422710