Selective Spectrophotometric Determination of Ftorafur with Phloroglucinol

Selective Spectrophotometric Determination of Ftorafur with Phloroglucinol

A new absorptiometric procedure for the determination of Ftorafur in pharmaceutical formulations is presented, based on the reaction of Ftorafur with a mineral acid-containing phloroglucinol solution. Absorbance readings at 430 nm obey Lambert-Beer's law within the concentration range from 4.00...

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Veröffentlicht in:Analytical letters 1981-01, Vol.14 (2), p.119-128
Hauptverfasser: Fábregas, J. L., Beneyto, J. E.
Format: Artikel
Sprache:eng
Schlagworte:
4-hydroxybutyraldehyde
Ftorafur
spectrophotometry
tetrahydrofuran derivatives phloroglucinol
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Zusammenfassung:A new absorptiometric procedure for the determination of Ftorafur in pharmaceutical formulations is presented, based on the reaction of Ftorafur with a mineral acid-containing phloroglucinol solution. Absorbance readings at 430 nm obey Lambert-Beer's law within the concentration range from 4.00 to 28.00 μg ml −1 . The method is operationally simple, precise and selective. A suggested mechanism is proposed.
ISSN:0003-2719
1532-236X
DOI:10.1080/00032718108081387