Subcutaneous Inflammatory Reaction to a Synthetic Auditory Ossicle (Bioceram®) in Rats
Cellular response and inflammatory reaction to synthetic auditory ossicle (Bioceram®) made from aluminium oxide are investigated. Local inflammatory effects are important in wound healing and in determining biocompatibility of an implant, necessitating the study of biologic effects of implants, espe...
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| Veröffentlicht in: | Acta oto-laryngologica 1999, Vol.119 (1), p.83-88 |
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| container_end_page | 88 |
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| container_issue | 1 |
| container_start_page | 83 |
| container_title | Acta oto-laryngologica |
| container_volume | 119 |
| creator | Qing Ye, Katsuichiro Ohsaki, Kunio Ii, Dong-Jun Li, Chun-Sheng Zhu, Yasuhiko Yamashita, Satoru Tenshin, Teruko Takano-Yamamoto |
| description | Cellular response and inflammatory reaction to synthetic auditory ossicle (Bioceram®) made from aluminium oxide are investigated. Local inflammatory effects are important in wound healing and in determining biocompatibility of an implant, necessitating the study of biologic effects of implants, especially inflammation and fibrous capsule formation. Bioceram® discs were implanted subcutaneously in the interscapular region of rats for various periods of time, ranging from 1 day to 300 days. Histological sections 6 |
| doi_str_mv | 10.1080/00016489950181990 |
| format | Article |
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Local inflammatory effects are important in wound healing and in determining biocompatibility of an implant, necessitating the study of biologic effects of implants, especially inflammation and fibrous capsule formation. Bioceram® discs were implanted subcutaneously in the interscapular region of rats for various periods of time, ranging from 1 day to 300 days. Histological sections 6</description><identifier>ISSN: 0001-6489</identifier><identifier>EISSN: 1651-2251</identifier><identifier>DOI: 10.1080/00016489950181990</identifier><identifier>PMID: 10219391</identifier><identifier>CODEN: AOLAAJ</identifier><language>eng</language><publisher>Stockholm: Informa UK Ltd</publisher><subject>Aluminum Oxide - toxicity ; Animals ; Biocompatible Materials - toxicity ; Biological and medical sciences ; Ceramics - toxicity ; Durapatite - toxicity ; Female ; Foreign-Body Reaction - pathology ; Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics ; Medical sciences ; Microscopy, Electron, Scanning ; Ossicular Prosthesis ; Rats ; Rats, Wistar ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the upper aerodigestive tract ; Technology. Biomaterials. 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Local inflammatory effects are important in wound healing and in determining biocompatibility of an implant, necessitating the study of biologic effects of implants, especially inflammation and fibrous capsule formation. Bioceram® discs were implanted subcutaneously in the interscapular region of rats for various periods of time, ranging from 1 day to 300 days. Histological sections 6</description><subject>Aluminum Oxide - toxicity</subject><subject>Animals</subject><subject>Biocompatible Materials - toxicity</subject><subject>Biological and medical sciences</subject><subject>Ceramics - toxicity</subject><subject>Durapatite - toxicity</subject><subject>Female</subject><subject>Foreign-Body Reaction - pathology</subject><subject>Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics</subject><subject>Medical sciences</subject><subject>Microscopy, Electron, Scanning</subject><subject>Ossicular Prosthesis</subject><subject>Rats</subject><subject>Rats, Wistar</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the upper aerodigestive tract</subject><subject>Technology. Biomaterials. 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Maxillofacial surgery. Dental surgery. Orthodontics</topic><topic>Medical sciences</topic><topic>Microscopy, Electron, Scanning</topic><topic>Ossicular Prosthesis</topic><topic>Rats</topic><topic>Rats, Wistar</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the upper aerodigestive tract</topic><topic>Technology. Biomaterials. 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Local inflammatory effects are important in wound healing and in determining biocompatibility of an implant, necessitating the study of biologic effects of implants, especially inflammation and fibrous capsule formation. Bioceram® discs were implanted subcutaneously in the interscapular region of rats for various periods of time, ranging from 1 day to 300 days. Histological sections 6</abstract><cop>Stockholm</cop><pub>Informa UK Ltd</pub><pmid>10219391</pmid><doi>10.1080/00016489950181990</doi><tpages>6</tpages></addata></record> |
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| ispartof | Acta oto-laryngologica, 1999, Vol.119 (1), p.83-88 |
| issn | 0001-6489 1651-2251 |
| language | eng |
| recordid | cdi_crossref_primary_10_1080_00016489950181990 |
| source | MEDLINE; Taylor & Francis:Master (3349 titles); Taylor & Francis Medical Library - CRKN |
| subjects | Aluminum Oxide - toxicity Animals Biocompatible Materials - toxicity Biological and medical sciences Ceramics - toxicity Durapatite - toxicity Female Foreign-Body Reaction - pathology Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics Medical sciences Microscopy, Electron, Scanning Ossicular Prosthesis Rats Rats, Wistar Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the upper aerodigestive tract Technology. Biomaterials. Equipments Time Factors |
| title | Subcutaneous Inflammatory Reaction to a Synthetic Auditory Ossicle (Bioceram®) in Rats |
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