Subcutaneous Inflammatory Reaction to a Synthetic Auditory Ossicle (Bioceram®) in Rats

Cellular response and inflammatory reaction to synthetic auditory ossicle (Bioceram®) made from aluminium oxide are investigated. Local inflammatory effects are important in wound healing and in determining biocompatibility of an implant, necessitating the study of biologic effects of implants, espe...

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Veröffentlicht in:	Acta oto-laryngologica 1999, Vol.119 (1), p.83-88
1. Verfasser:	Qing Ye, Katsuichiro Ohsaki, Kunio Ii, Dong-Jun Li, Chun-Sheng Zhu, Yasuhiko Yamashita, Satoru Tenshin, Teruko Takano-Yamamoto
Format:	Artikel
Sprache:	eng
Schlagworte:	Aluminum Oxide - toxicity Animals Biocompatible Materials - toxicity Biological and medical sciences Ceramics - toxicity Durapatite - toxicity Female Foreign-Body Reaction - pathology Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics Medical sciences Microscopy, Electron, Scanning Ossicular Prosthesis Rats Rats, Wistar Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the upper aerodigestive tract Technology. Biomaterials. Equipments Time Factors
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Zusammenfassung:	Cellular response and inflammatory reaction to synthetic auditory ossicle (Bioceram®) made from aluminium oxide are investigated. Local inflammatory effects are important in wound healing and in determining biocompatibility of an implant, necessitating the study of biologic effects of implants, especially inflammation and fibrous capsule formation. Bioceram® discs were implanted subcutaneously in the interscapular region of rats for various periods of time, ranging from 1 day to 300 days. Histological sections 6
ISSN:	0001-6489 1651-2251
DOI:	10.1080/00016489950181990