Nicotine-induced Endocytosis of Amiloride-sensitive Sodium Channels in Human Nasal Epithelium

In previous studies we developed and introduced a method to examine the transport mechanisms of ions in primary cell cultures of human nasal epithelium. In the current study, substances, especially nicotine, that influence these mechanisms are investigated. Specimens of nasal and paranasal epitheliu...

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Veröffentlicht in:Acta oto-laryngologica 2000-01, Vol.120 (2), p.286-290
Hauptverfasser: T, Klimek, H, Glanz, C, Ruckes-Nilges, W, Van Driessche, M, Weber W
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container_title Acta oto-laryngologica
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creator T, Klimek
H, Glanz
C, Ruckes-Nilges
W, Van Driessche
M, Weber W
description In previous studies we developed and introduced a method to examine the transport mechanisms of ions in primary cell cultures of human nasal epithelium. In the current study, substances, especially nicotine, that influence these mechanisms are investigated. Specimens of nasal and paranasal epithelium of patients treated by endonasal surgery because of chronic sinusitis (
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subjects Amiloride - pharmacology
Calcium - metabolism
Cells, Cultured
Endocytosis - drug effects
Endocytosis - physiology
Humans
Membrane Potentials - drug effects
Nasal Mucosa - drug effects
Nasal Mucosa - physiopathology
Nicotine - pharmacology
Protein Kinase C - physiology
Smoking - physiopathology
Sodium Channels - drug effects
Sodium Channels - physiology
title Nicotine-induced Endocytosis of Amiloride-sensitive Sodium Channels in Human Nasal Epithelium
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