Complex of Pregnancy-associated Plasma Protein-A and the Proform of Eosinophil Major Basic Protein

Pregnancy-associated plasma protein-A (PAPP-A) is a metzincin superfamily metalloproteinase responsible for cleavage of insulin-like growth factor-binding protein-4, thus causing release of bound insulin-like growth factor. PAPP-A is secreted as a dimer of 400 kDa but circulates in pregnancy as a di...

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Veröffentlicht in:	The Journal of biological chemistry 2003-01, Vol.278 (4), p.2106-2117
Hauptverfasser:	Overgaard, Michael T., Sørensen, Esben S., Stachowiak, Damian, Boldt, Henning B., Kristensen, Lene, Sottrup-Jensen, Lars, Oxvig, Claus
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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