Biosynthesis of Vitamin B6 inRhizobium
The biosynthetic pathway of pyridoxol (vitamin B6) in Rhizobium was clarified by studies on the incorporation of 13C- or 15N-labeled precursors into pyridoxol or its biosynthetic intermediates. Pyridoxol was formed by ring closure of two compounds, 1-deoxy-d-xylulose and 4-hydroxy-l-threonine. The f...
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Veröffentlicht in: | The Journal of biological chemistry 2000-04, Vol.275 (15), p.11300-11305 |
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Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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Zusammenfassung: | The biosynthetic pathway of pyridoxol (vitamin B6) in Rhizobium was clarified by studies on the incorporation of 13C- or 15N-labeled precursors into pyridoxol or its biosynthetic intermediates. Pyridoxol was formed by ring closure of two compounds, 1-deoxy-d-xylulose and 4-hydroxy-l-threonine. The former was formed from d-glyceraldehyde and pyruvate through decarboxylation of pyruvate, and the latter from glycine and glycolaldehyde. |
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ISSN: | 0021-9258 1083-351X |
DOI: | 10.1074/jbc.275.15.11300 |