Developmentally Excised DNA Sequences in Euplotes crassus Capable of Forming G Quartets

Tens of thousands of DNA segments are eliminated by DNA breakage and rejoining events during the formation of a new macronucleus in the hypotrichous ciliated protozoan Euplotes crassus. This study presents evidence for a class of eliminated sequences referred to as telomeric-repeatlike internal elim...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1995-03, Vol.92 (6), p.1979-1983
1. Verfasser:	Klobutcher, Lawrence A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Composition Base Sequence Cell Line Chromosomes Deoxyribonucleic acid DNA DNA Primers DNA, Protozoan - genetics DNA, Protozoan - isolation & purification Euplotes - genetics Euplotes crassus Gels Genetics Macronucleus Methylation Molecular Sequence Data Molecules Nucleic acids Oligonucleotides Polymerase chain reaction Polymerase Chain Reaction - methods Repetitive Sequences, Nucleic Acid Restriction Mapping Sulfuric Acid Esters Telomere - physiology Telomeres
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Beschreibung
Zusammenfassung:	Tens of thousands of DNA segments are eliminated by DNA breakage and rejoining events during the formation of a new macronucleus in the hypotrichous ciliated protozoan Euplotes crassus. This study presents evidence for a class of eliminated sequences referred to as telomeric-repeatlike internal eliminated sequences (TelIESs). TelIESs are shorter (
ISSN:	0027-8424 1091-6490
DOI:	10.1073/pnas.92.6.1979