Disassembly of mitotic checkpoint complexes by the joint action of the AAA-ATPase TRIP13 and p31 comet

The mitotic checkpoint system has an important role to ensure accurate segregation of chromosomes in mitosis. This system regulates the activity of the ubiquitin ligase Anaphase-Promoting Complex/Cyclosome (APC/C) by the formation of a negatively acting Mitotic Checkpoint Complex (MCC). When the che...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2014-08, Vol.111 (33), p.12019-12024
Hauptverfasser:	Eytan, Esther, Wang, Kexi, Miniowitz-Shemtov, Shirly, Sitry-Shevah, Danielle, Kaisari, Sharon, Yen, Tim J., Liu, Song-Tao, Hershko, Avram
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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