Role of ABC Transporters in Secretion of Cholesterol from Liver into Bile

Role of ABC Transporters in Secretion of Cholesterol from Liver into Bile

Small discusses research that has proven that all biliary lipids are secreted in a controlled way by ABC transporters, and that the physical chemistry of the lipid interactions probably occurs within the lumen of the canniliculus and biliary ducts. Several studies into this theory are discussed.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2003-01, Vol.100 (1), p.4-6
1. Verfasser: Small, Donald M.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
ATP-Binding Cassette Transporters - metabolism
Bile
Bile - physiology
Bile acids
Biochemistry
Cholesterol - metabolism
Cholesterols
Commentaries
Fatty acids
Lipid Bilayers
Lipids
Liver
Liver - physiology
Medical research
Micelles
P branes
Phospholipids
Secretion
Solubility
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Small discusses research that has proven that all biliary lipids are secreted in a controlled way by ABC transporters, and that the physical chemistry of the lipid interactions probably occurs within the lumen of the canniliculus and biliary ducts. Several studies into this theory are discussed.
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.0237205100