The relationship between the structure and anti-AIDS activity of polyhydroxypiperidines and polyhydroxypyrrolidines

A mathematical model has been constructed for the anti-AIDS activity of polyhydroxypiperidines and polyhydroxypyrrolidines based on a systematic search of such sets of pairs of fragments, whose presence or absence in the molecules studied considerably affects their biological activity.

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Veröffentlicht in:Mendeleev communications 1996, Vol.6 (1), p.27-29
Hauptverfasser: Makeev, Gennady M., Kumskov, Mikhail I.
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container_title Mendeleev communications
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creator Makeev, Gennady M.
Kumskov, Mikhail I.
description A mathematical model has been constructed for the anti-AIDS activity of polyhydroxypiperidines and polyhydroxypyrrolidines based on a systematic search of such sets of pairs of fragments, whose presence or absence in the molecules studied considerably affects their biological activity.
doi_str_mv 10.1070/MC1996v006n01ABEH000564
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title The relationship between the structure and anti-AIDS activity of polyhydroxypiperidines and polyhydroxypyrrolidines
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